Category Archives: Dietary adaptations

Faster than Fisher

There’s a simple model of the spread of an advantageous allele:  You take σ, the typical  distance people move in one generation, and s,  the selective advantage: the advantageous allele spreads as a nonlinear wave at speed  σ * √(2s).  … Continue reading

Posted in Denisovans, Dietary adaptations, European Prehistory, Evolutionary Medicine, Genetics, Indo-European, Linguistics, Neanderthals, Skin color | Tagged | 74 Comments

Centum and Satem

I may well be wrong, but there’s no point in waiting until they dig up and sequence every last body in Eurasia. Time to stick my neck out. Here’s my current best guess concerning the Indo-European expansion: It all started … Continue reading

Posted in Dietary adaptations, European Prehistory, Genetics, Indo-European, Linguistics | Tagged , , , | 99 Comments

Ketosis as a way of life

There’s a new article out in ASHG that discusses a regional selective sweep in CPT1A, carnitine palmitoyltransferase 1A, which plays an essential role in fatty acid metabolism. A mutation has become extremely common, with a gene frequency > 50%, in … Continue reading

Posted in Dietary adaptations, Eskimo, Genetics | Tagged | 65 Comments

Let George Do It

I was thinking about how people would have adapted to local differences in essential micronutrients, stuff like iodine, selenium, manganese, molybdenum, zinc, etc. Australia, for example,  hasn’t had much geological activity in ages and generally has mineral-poor soils. At first … Continue reading

Posted in Australian Aboriginals, Dietary adaptations | Tagged | 76 Comments