I was thinking about how people would have adapted to local differences in essential micronutrients, stuff like iodine, selenium, manganese, molybdenum, zinc, etc. Australia, for example, hasn’t had much geological activity in ages and generally has mineral-poor soils. At first I thought that Aboriginals, who have lived in such places for a long time, might have developed better transporters, etc – ways of eking out scarce trace elements.
Maybe they have, but on second thought, they may not have needed to. Sure, the Aboriginals were exposed to these conditions for tens of thousands of years, but not nearly as long as kangaroos and wombats have been. If those animals had effective ways of accumulating the necessary micronutrients, hunter-gatherers could have solved their problems by consuming local fauna. Let George do it, and then eat George.
The real problems should occur in people who rely heavily on plant foods (European farmers) and in their livestock, which are generally not adapted to the mineral-poor environments. If I’m right, even in areas where sheep without selenium supplements get white muscle disease (nutritional muscular dystrophy), indigenous wildlife should not.