Monthly Archives: November 2012

There’s a new paper out in Nature, by Wenqing Fu and many other people, about the recent origin of most variants in protein-coding genes. They conclude that most are less than 5-10,000 year old – younger in Europeans than in … Continue reading →

Once upon a time, I was working at Hughes Aircraft, analyzing missile guidance sensors and trying to design laser weapons.  My fellow engineers thought I had other strengths -  I was a halfway decent pinochle player.  Some thought my abilities … Continue reading →

There is an insightful and data-rich blog called hbd* chick that is well worth our reading. A recent post discusses Steven Pinker’s new book about the decline of violence. I haven’t read the book, but the discussion on hbd* chick’s … Continue reading →

In a review in the NYRoB, Richard Lewontin says “The other exception to random inheritance is not in the chromosomes, but in cellular particles called ribosomes that contain not DNA but a related molecule, RNA, which has heritable variation and … Continue reading →

I showed my small son Sam the Bridges of Königsberg problem: The problem is to find a walk through the city that crosses each bridge once and only once. Turns out that this is impossible: I told Sam, but he … Continue reading →

In two recent paper,  Gerald Crabtree says two correct things.  He says that the brain is complex, depends on the correct functioning of many genes, and is thus particularly vulnerable to genetic load.  Although he doesn’t use the phrase “genetic … Continue reading →

A number of people have argued that there can’t be real evolutionary change in less than some huge amount of time – 50k years, 100k years, basically whatever number  they need to win an argument.  That’s all bullshit.  On the … Continue reading →